Mast Cell Activation Disorder
Extensive functional assessment for MCAS and histamine intolerance conditions using precision medicine and functional approaches.
What is Mast Cell Activation Syndrome?
Certain cell types create immediate allergic reactions; these are called mast cells. When triggered, they release a substance called a mediator, which is stored inside them or manufactured by them. During a mast cell allergic reaction, the antibody IgE (immunoglobin) triggers cells that release chemicals and cause an allergic reaction.
Mastocytosis can cause a wide range of very unpleasant symptoms — some can be quite debilitating, affecting multiple systems of the body at once, making a person feel quite ill very suddenly. It can present in familial groups including adults and children, manifesting a wide range of symptoms that leave doctors mystified.
It is a tough illness to diagnose and a tougher one to live with, but the right team of doctors can help make life enjoyable again.
Types of Mast Cell Reactions
Normal Mast Cell Reactions
IgE antibodies trigger cells that release chemicals causing allergic reactions in the nose, lungs, throat, or skin. Each type of IgE has a specific response for each type of allergen — which is why some people are allergic to cat dander and others to dog fur.
Secondary Activation
Some mast cells must be activated by external substances like medications, infections, or insect/reptile venom. These are normal reactions triggered by external stimuli.
Defective Mast Cells (Mastocytosis)
Occasionally mast cells become defective and release mediators due to internal crossed signals. These mutations produce more and more mast cell clones that can grow out of control, leading to mastocytosis — basically a benign tumor of sorts.
Idiopathic Mast Cell Activation
A condition in which a patient suffers repeated episodes with symptoms of anaphylaxis — hives, rapid pulse, lowered blood pressure, and passing out — without a clear external trigger.
Systemic Effects
Mast cell activation can affect multiple organ systems simultaneously, causing a wide range of symptoms that can strike suddenly and without warning.
Skin
Cardiovascular
Respiratory
Gastrointestinal
Neurologic
Musculoskeletal
Potential Triggers of Mast Cell Activation
By all means these are not certain triggers, however they are thought to be potential MAST triggers:
Management Options
Management options for mast cell activation at Natural Balance Wellness Medical Center focus on identifying root causes and reducing systemic reactivity.
Precision Medicine
Advanced genomic testing and biomarker analysis to identify the specific mechanisms driving your mast cell activation and develop targeted interventions.
Functional & Integrative Medicine
A whole-body approach addressing underlying triggers, gut health, environmental factors, and immune system regulation to reduce mast cell reactivity.
We Are Here to Help You!
For a personalized assessment and management plan unique to you and your needs, get in touch with our team today.